New Macrocycles Bind and Transport Anions with High Efficiency

Scientists have crafted novel macrocycles, composed of aromatic rings and amide bonds, that adeptly capture and transport anions. Their rigid structure compels hydrogen bond donors inward, forming a highly electropositive cavity ideal for anion binding. Moreover, these macrocycles can integrate into bio-membranes, facilitating anion transport across cell membranes. This breakthrough holds promise for treating conditions like cystic fibrosis, marked by faulty anion transport.