Researchers at Stockholm University and SciLifeLab have developed a novel technique to pinpoint microRNA targets in individual cells, eliminating the need for millions of cells. This advancement enables the study of microRNAs in intricate tissues like the brain. MicroRNAs, which control gene activity by binding to and degrading messenger RNA (mRNA), govern over 60% of human genes and play pivotal roles in various biological processes, including diseases like cancer. This breakthrough promises to transform our comprehension of microRNA’s gene-regulating abilities and their impact on human well-being.