Artificial = contrived by art rather than nature or unreal or not of natural origin: ‘I still prefer sugar to all those artificial sweeteners’; ‘Most people look better under artificial light.’
Man-made = made or caused by people, although sometimes having a natural appearance: ‘This canal is the longest man-made waterway in the world.’
Synthetic = not natural but made by a chemical process: ‘Many old herbal remedies have been replaced by synthetic drugs.’
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